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Accueil du site > Évènements > Séminaires > Séminaires IUSTI > Archives IUSTI > 2023

Vendredi 6 janvier 2023 / IUSTI

publié le

Séminaire IUSTI

Migration of single immune cells in vitro : mechanisms of propulsion and guidance

Orateur : Olivier Theodoly – LAI Inserm, Marseille

Abstract : We use microfabricated tools and human primary lymphocytes to decipher amoeboid cell migration in vitro. Concerning propulsion, mammalian cells usually need adhesion or friction with a substrate to move. We show here that lymphocytes can swim and we propose a new mechanism of molecular paddling. Concerning guidance, we present new phenotypes of mechanical guidance by flow and of chemical guidance by adhesion molecules, and we discuss their active or passive nature.

Date et lieu : vendredi 6 janvier à 11h00, salle 250 / IUSTI

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